The laboratory of Markus Grompe investigates the biology of liver and pancreas stem cells. This work has important implications for the development of embryonal (pediatric) and adolescent cancers, namely hepatoblastoma and hepatocellular carcinoma. Dr. Grompe is a medical geneticist with expertise in metabolic disorders and Fanconi Anemia. He is also Director of the Oregon Stem Cell Center and the Pape' Family Pediatric Research Institute.
[ right: an exciting recent study published in Nature, describing an unprecedented biological process whereby normal liver cells are capable of increasing their chromosome number, without apparent predisposition to cancer developing. ]